Latin America recorded $730 billion in crypto volume in 2025. Across the region, 57.7 million people now own some form of digital currency rankingslatam, a base that is growing faster than anywhere else in the world
As institutional capital arrives and regulation matures, these are the publicly traded names investors are watching closest.
Why LATAM is a crypto powerhouse right now
Top LATAM crypto stocks to watch
1. Nu Holdings (NYSE: NU)
Digital banking · 127M users across Brazil, Mexico and Colombia
Nubank could be one of the most direct listed proxies for LATAM's fintech and crypto boom. The company integrated cryptocurrency trading directly into its Nu app and partnered with Lightspark to embed the Bitcoin Lightning Network for faster and more cost-effective Bitcoin transactions.
In Q3 2025, revenue jumped 42% year-on-year to $4.17 billion, customer deposits rose 37% to $38.8 billion, and gross profit was up 35% to $1.81 billion.
The stock has returned roughly 36% over the past year and tripled the S&P 500's returns over the last three years. The company dominates Brazil, with over 60% of the adult population using Nubank.
Nu Holdings also recently secured conditional approval to launch Nubank N.A., a US national digital bank. However, the announcement triggered a pullback, with investors cautious about capital deployment timelines and expansion costs.
UBS has lowered its price target to $17.20, citing some market caution despite positive operational shifts.
What to watch
- Credit quality trends in Brazil and Mexico.
- Pace of USDC adoption via Nubank rewards.
- US bank charter timeline and early cost disclosures.
2. MercadoLibre (NASDAQ: MELI)
E-Commerce/Fintech · 18 countries across Latin America
MercadoLibre is not a pure crypto play, but Mercado Pago (its fintech arm) has become one of the most important financial rails in LATAM. The company holds around 570 BTC on its balance sheet as a hedge against regional inflation, and has issued its own US dollar-pegged stablecoin, Meli Dólar.
Full year 2025 net revenue from Mercado Pago reached $12.6 billion, up 46% year-on-year, while total payment volume hit $278 billion, up 41%. Fintech monthly active users have grown close to 30% for ten consecutive quarters, and the credit portfolio nearly doubled to $12.5 billion year-on-year.
The catch for MercadoLibre is profitability. Overall margin compression of 5–6% is attributed to persistent investments in free shipping, credit card expansion, first-party commerce, and cross-border trade.
The stock has declined around 14.5% over the past six months, with the market repricing the stock around what management has framed as a deliberate investment phase heading into 2026.
The longer-term case remains compelling. Mercado Pago has introduced crypto-asset management and insurance products across its core markets, positioning it less as an e-commerce company and more as a full-scale digital bank with crypto infrastructure built in.
What to watch
- Mercado Pago loan loss trends and credit portfolio quality.
- Stablecoin integration and crypto volume through its payment network.
- Whether the Argentina credit card launch can reach profitability.

3. Méliuz (B3: CASH3.SA)
Fintech/Bitcoin treasury · Brazil's first listed Bitcoin treasury company
Méliuz is the most direct equity expression of the corporate Bitcoin treasury trend in LATAM. In early 2025, Méliuz became the first publicly traded company in Latin America to formally adopt a Bitcoin treasury strategy, receiving shareholder approval to allocate cash reserves toward Bitcoin accumulation.
Rather than issuing cheap dollar-denominated debt to buy BTC, Méliuz uses share issuance and operational cash flow. The company also sells cash-secured put options on Bitcoin to generate yield, a playbook borrowed from Japanese Bitcoin treasury firm Metaplanet, keeping 80% of BTC holdings in cold storage
CASH3 essentially acts as a leveraged vehicle for BTC exposure, capturing upside intensely in bull cycles, but generating greater volatility on the way down, especially where debt is involved.
The stock surged approximately 170% in May 2025 following the announcement of the Bitcoin strategy. However, it has since pulled back to its April 2025 levels, broadly tracking Bitcoin's price action and highlighting the stock's volatility.
What to watch
- Bitcoin price direction.
- BTC per share metric.
- Expansion of yield-generation strategies
- Any moves to list shares internationally.

4. OranjeBTC (B3: OBTC3.SA)
Pure-play Bitcoin treasury · LATAM's largest corporate Bitcoin holder
Where Méliuz is a fintech business that also holds Bitcoin, OranjeBTC is the opposite: a company whose entire purpose is Bitcoin accumulation.
The company listed on B3 in October 2025 through a reverse merger with education firm Intergraus, marking Brazil's first public debut of a firm whose business model centres entirely on Bitcoin accumulation.
OranjeBTC currently holds over 3,650 BTC and raised nearly $385 million in Bitcoin, with backing from notable investors including the Winklevoss brothers, Adam Back, FalconX, and Ricardo Salinas.
Its $210 million financing round was led by Itaú BBA, the investment arm of Brazil's largest bank, in a significant vote of institutional confidence.
In 2026, OBTC3 has fallen around 32% year-to-date, making it the hardest-hit of the two Brazilian Bitcoin treasury stocks. The stock hit an all-time high of 29.00 BRL on its listing day (October 7, 2025) and an all-time low of 6.06 BRL in February 2026.
It currently trades around 7.06 BRL, a steep discount to its debut, but one that closely mirrors Bitcoin's own pullback from peak levels.
OranjeBTC is the most volatile name on this list and should be treated as a high-beta Bitcoin vehicle. Liquidity is thinner than established names.
What to watch
- Bitcoin per share trajectory.
- Any capital raises or new BTC purchases.
- Potential international listing ambitions.
- How the market-value net asset value (mNAV) discount/premium evolves relative to Bitcoin's price.
5. Hashdex — HASH11 (B3: HASH11)
Crypto Asset Management · Brazil's leading crypto ETF issuer
Hashdex offers a different kind of exposure to crypto. Rather than a single company's balance sheet or business strategy, HASH11 is a diversified basket of crypto assets wrapped in the familiarity of a regulated Brazilian ETF structure.
Brazil hosts 22 ETFs offering full or partial exposure to crypto assets, with Hashdex funds attracting 180,000 investors and daily transaction volumes averaging R$50 million.
Hashdex launched the world's first spot XRP ETF (XRPH11) on Brazil's B3 in April 2025, tracking the Nasdaq XRP Reference Price Index and allocating at least 95% of net assets to XRP.
The company also operates single-asset ETFs for Bitcoin (BITH11), Ethereum (ETHE11) and Solana (SOLH11), alongside its flagship HASH11 multi-asset index fund.
In mid-2025, Hashdex launched a hybrid Bitcoin/Gold ETF (GBTC11) that dynamically adjusts allocations between the two assets.
For investors who want diversified crypto market exposure rather than single-asset risk, HASH11 is the most accessible on-ramp through Brazil's regulated equity infrastructure.
However, as a multi-asset crypto index, HASH11 is still subject to the broad performance of digital asset markets. And unlike the equity names on this list, there is no operating business creating independent value.
What to watch
- Crypto market sentiment broadly.
- Potential expansion of Hashdex products into the US market.
- AUM growth as institutional adoption accelerates in Brazil.
- Relative performance of HASH11 vs single-asset alternatives.

What to watch next
Institutional infrastructure is still in early innings — Deutsche Börse's Crypto Finance Group entered LATAM in early 2026, and local exchanges have opened over 200 BRL-denominated trading pairs since 2024. The pace of that buildout will set the tone for all five names.
Regulatory progress in Brazil, Mexico, and Chile is the key enabler for the next wave of capital. Any setbacks would hit the higher-beta names like OBTC3 and CASH3 hardest.
Stablecoin volume is the region's most reliable real-time signal. Despite a global slowdown in early 2025, LATAM still recorded $16.2 billion in trading volume between January and May, up 42% year-on-year. Watch whether that momentum holds — a reacceleration lifts all five; a reversal pressures them equally.















